146 Vital ® AF 1.2 Cal Peptide-Based, Therapeutic Nutrition for Inflammation and Tolerance Usage VITAL AF 1.2 CAL is peptide-based therapeutic nutrition that provides complete, balanced nutrition for long- or short-term patients who require tube feeding and are experiencing malabsorption, maldigestion, or impaired GI function and/or GI intolerance. • For tube or oral feeding. • For supplemental or sole-source nutrition. • Use under medical supervision. Features • Designed to promote tolerance: • Hydrolyzed peptide-based protein system. • Medium chain triglyeride/fish oil structured lipid, a well-tolerated 1,2 and absorbed 1 next-generation fat to promote absorption of fatty acids. • 1.2 g of scFOS/8 fl oz (5.1 g/L). scFOS are prebiotic fibers that stimulate the growth of beneficial bacteria in the colon. 3-5 • Omega-3 fatty acids EPA (2.7 g/L) and DHA (1.1 g/L) from fish oil to help modulate inflammation and support immune function. 6,7 • 75 g/L protein to meet the increased protein needs of stressed patients (greater than or equal to 1.2 g/kg) and support healing. 8 • 1500 Calories (1250 mL) provide at least 100% of the RDIs for 25 essential vitamins and minerals. • Contains at least 100% of the RDI for vitamin D per 1500 Calories to: a) Help maintain normal circulating levels of vitamin D, which has been shown to be decreased in critically ill patients 9,10 /patients with malabsorption 11 b) Help meet the increased vitamin D needs of critically ill patients. 9-11 • Contains elevated levels of the antioxidants vitamins C & E and selenium to help reduce free radical damage. 12,13 • Gluten-free, suitable for lactose intolerance. Precautions • Not for IV use. • Not for people with galactosemia. Availability List No. NDC Format Code — 33.8-fl oz ( 1.0-L) Ready to Hang Prefilled Container; 8/case Ready to Hang . . . . . . . . . . . . . . . . . . . . . . . . . 62715 . . . . . . . . . . . . 70074-0627-16 — 8.0-fl oz ( 237.0-mL) Recloseable Carton; 24/case Vanilla . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64828 . . . . . . . . . . . 70074-0648-26 1 Kenler AS, et al. Ann Surg. 1996;223(3):316-333. 2 McKenna MC, et al. J Pediatr Gastroenterol Nutr. 1985;4(1):45-51. 3 Bornet FR, et al. Nutr Rev. 2002;60(11):326-334. 4 Tokunaga T, et al. Bifidus. 1993;6(2):143-150. 5 Bouhnik Y, et al. Nutr J. 2007;6:42-48. 6 Calder PC. Prostaglandins Leukot Essent Fatty Acids. 2008;79(3-5):101-108. 7 Calder PC. Clin Nutr. 2010;29(1):5-12. 8 McClave S, et al. JPEN J Parent Enteral Nutr. 2016;40(2):159-211. 9 Lee P, et al. Intensive Care Med. 2009;35(12):2028-2032. 10 Lee P, et al. N Engl J Med. 2009;360(18):1912-1914. 11 Kuwabara A, et al. Osteoporos Int. 2009;20(6):935-942. 12 I nstitute of Medicine (US) Panel on Dietary Antioxidants and Related Compounds. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington (DC): National Academies Press (US);2000. 13 Sies H. Redox Biol. 2015;4:180-183.